Biomarking the way

On Parmenides' Poem: "The Way of Truth" and "The Way of Opinion"

Serotonergic PET in temporal lobe epilepsy: biomarking or etiologic mapping?

PET and selected ligands offer brain mapping for a panoply of neuronal receptors and other important brain molecules. Neurochemically specific PET studies have yielded numerous biomarkers of hippocampal and extrahippocampal dysfunction, which often have been used to study groups with temporal lobe epilepsy (TLE). Etiologies and the development of epilepsy are poorly understood in TLE, however. ...

‘Biomarking’ infection during continuous renal replacement therapy: still relevant?

We greatly appreciated the recent research article by Park and colleagues in Critical Care showing that procalcitonin (PCT) is not superior to C-reactive protein (CRP) as a marker for infection in renal impairment [1]. Additionally, we would like to comment on the validity of CRP and PCT measurement during continuous renal replacement therapy (CRRT). Both acute-phase proteins are indeed effecti...

The Way Forward Is the Way Back

“T viewer should see the object as I saw it, but with a lot of room for his own interpretation....The painting is like a very clear mirror which is barely visible but unmistakably there,” reflects Spanish painter Antonio López García (b. 1936) (1). “I am nostalgic for an art of our times in which a greater number of people can participate” (1). Part of a contemporary movement rooted in the trad...

W2: “Discogenic Pain and the Way to Treatment”

The exact differentiation of the back pain and its backgrounds made the base of much research. Various triggers also have different pathomechanism. This background is used after accurate detection in the treatment of back pain. Discogenic pain is a particular challenge in pathobiochemistry and therapy.